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The case series published in SAGE Open Medical Case Reports showed that patients who maintained exercise protocols of 3 to 5 resistance training sessions per week while on GLP-1 therapy preserved lean mass successfully, with some even gaining muscle while losing fat

Ethics declarations Ethics approval and consent to participate This study was performed in accordance with the regulations of Chongqing Medical University Standing Committee on human biomedical research and animal experiments, and were approved by the Institutional Committee

Digestive Discomfort : Oral use may cause nausea, bloating, or mild abdominal cramps

AMPK as energy sensor and one important metabolic pathway decreases fatty acid synthase and acetyl CoA carboxylase (ACC) by suppressing SREBP-1c