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the mimics may be administered prior to exposure to a drug, chemical or medical procedure that is known or likely to cause neuronal damage

10.1016/j.neuroscience.2012.11.037 400

Estrogen-Induced Activation of Erk-1 and Erk-2 Requires the G Protein-Coupled Receptor Homolog, GPR30, and Occurs via Trans-Activation of the Epidermal Growth Factor Receptor through Release of HB-EGF