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Description

Mechanism of ghrelin-induced activation The comparison of the ghrelin-bound complex structure with the neutral antagonist-bound structure shows that the TM bundles at the extracellular portion are similar, except that the helix end of TM7 is tilted outward by ~5.5 (Fig

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Upregulation of non-tyrosine kinase (FER) in ovarian cancer promotes tumorigenesis by activating the PI3K-AKT pathway through the kinase-substrate mode of action between FER and insulin receptor substrate 4 (IRS4) (70)

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