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However, it has a short plasma half-life of 2030 min, necessitating continuous infusion over 812 h for 57 days a week, which significantly decreases patients compliance (Mobarra et al., 2016)

Evaluation of the efficacy and safety of amustaline/glutathione pathogen-reduced RBCs in complex cardiac surgery: the Red Cell Pathogen Inactivation (ReCePI) studyprotocol for a phase 3, randomized, controlled trial