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GHK-CU remains a research compound without official dosing guidelines, which means protocols rely on accumulated practitioner experience and extrapolation from laboratory studies

The phosphorylation of NF-B p65 at Ser536 in lung increased significantly after LPS administration compared with control group, while the treatment with GHK-Cu reduced phosphorylation of NF-B p65 at Ser536 in LPS + 10 g/g GHK-Cu group compared to the LPS group (Figure 8)

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Comparative effectiveness research with established therapies would help determine the relative benefits and risks of these peptides compared to current standard treatments and would inform evidence-based treatment decisions