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These effects are often dose-dependent and more prominent during initial administration

Mitochondrial biogenesis is enhanced by mTOR-mediated activity in the transcription and translation of nuclear-encoded mitochondrial RNAs and proteins as well as fusion and fission of preexisting organelles

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Nitric oxide is also essential in other bodily systems such as the immune and nervous systems, and plays a major role in chronic conditions and diseases such as erectile dysfunction and chronic inflammation