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showed that in the emergency department, the circulating concentration of syndecan-1, a marker of glycocalyx degradation, correlates with the fluid requirement, severity of sepsis, extent of organ dysfunction, and risk of mortality, but a direct relationship with glycocalyx degradation has not been identified (123)

There are risks, even when done with a supervised, experienced team, but this is a place where quality and experience matter.

Pyruvate kinase M2 regulates gene transcription by acting as a protein kinase

BMJ 341:c6764 Pearce B, Grant IS (2008) Acute liver failure following therapeutic paracetamol administration in patients with muscular dystrophies