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New insights into the pivotal role of the amygdala in inflammation-related depression and anxiety disorder

[17] Note: phosphorylation is a fundamental biochemical reaction catalyzed by kinases , a subclass of transferases

BPC-157, short for Body Protection Compound 157, is a synthetic peptide derived from a naturally occurring protein found in gastric juice

While Nrf2 and JAK2/STAT3 have protective roles, severe oxidative stress can also lead to their dysregulation or interaction with other pathways in ways that contribute to later-stage remodeling or inflammation (Mahdiani et al., 2022