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If you're considering it for cognitive enhancement, the evidence isn't there

It is thought that 5hmC is particularly crucial in the brain due to its high abundance there compared to other organs (Li and Liu, 2011) and its enrichment in synapse-related genes (Khare et al., 2012)

[DOI] [PMC free article] [PubMed] [Google Scholar] 255.Davis JF, Schurdak JD, Magrisso IJ, Mul JD, Grayson BE, Pfluger PT, Tschp MH, Seeley RJ, Benoit SC