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some of these cells create brainbody barriers (perineurial and subperineurial surface glial cells), others cover neuronal somata (cortex glia) and some ensheath synapses in neuropil (astroglia-like cells) 32,33

For lipophagy, the lipid droplets coated by a double membrane structure can be observed by transmission electron microscopy

Additionally, strategies such as low-dose optimization, structural analog design for enhanced CNS selectivity, and targeted drug delivery systems hold promise for improving Tozasertibs therapeutic index