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Experimental evidence suggests that ketone bodies exert both bioenergetic effects, such as enhancing mitochondrial ATP production [39, 40], and signaling effects mediated primarily by BHB [21, 37]

Using GAPDH as an internal reference, the relative expression levels of each gene were analyzed using the 2 CT method

Lipoic acid comes in two mirror image forms labeled R and S. The R form is the active form produced and used in living systems (Gomes 2014)