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Description

Johnston, Andrew Grigg, Michael J

To improve its efficiency and minimize the adverse effects, controlled stimuli-responsive nanosystem for on-demand drug release is highly desirable 2

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HGF, the ligand of c-MET, is secreted as a single chain 83 kDa precursor protein containing an N-terminal (N) domain, four consecutive kringle (K1K4) domains, and a serine protease homology (SPH) domain (Fig