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if fatigue persists despite normal B vitamin levels, ask your doctor to check for other causes

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In summary, based on the characteristic metabolic reprogramming of tumor cells, combination therapies that simultaneously target multiple metabolic pathways or synergize with other treatment modalities represent a systematic strategy to overcome the limitations of monotherapy, suppress tumor adaptation, and ultimately increase therapeutic efficacy

I.C.4.a.2 Assigning Diabetes Codes and Sequencing: E08 (DM due to underlying condition): Sequence the underlying condition FIRST (e.g., cystic fibrosis, Cushing syndrome), then E08.x