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Users who tolerate 0.5% for two weeks and immediately jump to 2% often encounter problems

and Guo, M., "Loss-of-function analysis suggests that Omi/HtrA2 is not an essential component of the pink1/parkin pathway in vivo", J

Ropinirole: Ropinirole, primarily used for Parkinson's disease and restless legs syndrome, has been used off-label for reducing tics

Science 267(5202):12751276 Xu X, Wang L, Luo Z, Ni Y, Sun H, Gao X, Wei S (2017) Facile and versatile strategy for construction of anti-inflammatory and antibacterial surfaces with polydopamine-mediated liposomes releasing dexamethasone and minocycline for potential implant applications