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JHU-083 markedly suppresses the recruitment of MDSCs by decreasing tumor-derived CSF3 levels via degradation of C/EBP, which in turn increases the numbers of proinflammatory TAMs and enhances antigen presentation to CD8(+) T cells, resulting in stronger T-cell responses 150

Fertility rate and number of liveborn The procedure was conducted as previously described 70

582 Obviously, ZIP4 knockdown combined with gemcitabine may be another promising novel approach for the treatment of PC metastasis and drug resistance

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