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Available from: Bonomini M, Del Vecchio L, Sirolli V, Locatelli F

Authors: Nadine Pomarede and Meera cnenaremouti Date: 2009 Abstract The skin is the bodys largest organ and its first line of defense

Interestingly, recent studies indicate that in the setting of ATII-induced hypertension, a downregulation of the dihydrofolate reductase was observed, which was accompanied by decreased vascular BH 4 levels and an uncoupled eNOS, 91 implicating a potential role of this salvage pathway in the development of hypertension