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In contrast, two other randomized exploratory trials used a higher dose of resveratrol (800 mg) for 12 weeks and found it reduced MMP-2, MMP-9, VEGF, and TNF- levels in ectopic endometrial tissue ( Mirzaei et al

However, excessive ROS and impaired antioxidant mechanisms will cause oxidative damage to lipids, proteins, DNA and other cellular components (Dorszewska et al., 2023)

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With limited available data on the protective effects of ginseng or its NPs against MTX-induced testicular toxicity, the findings of this study suggest that both ginseng and ginseng NPs protect against MTX-induced testicular toxicity in rats