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SKU: 12210696580
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Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and 1-methyl-4-phenylpyridinium ion on activities of the enzymes in the electron transport system in mouse brain

Results: BPV had a distinct profile of innate immune activation compared to the other ASOs tested

They also confirmed the findings of previous studies in implicating plasmin/plasminogen in the function of macrophagic endocytosis of fibrin, noting that plasminogen is needed for the fragmentation of fibrin to expose cellular binding sites for endocytic uptake but also that plasmin directly stimulates macrophage phagocytosis