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Probiotics as Lactocaseibacillus rhamnosus zz-1 can enhance tight junction protein expression (including ZO-1, occludin, and claudin-1) and promote epithelial barrier repair, thus limiting antigenic load and reducing systemic inflammation (Xu et al., 2023)

Owing to sharing the same nuclear NAD + pool, the ability of PARP1 to attenuate SIRT1 activity in an NAD + -dependent manner is also implicated in some other metabolic disorders

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