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doi: 10.1038/s41419-023-05716-0 132 KangLPHuangHJXuCChenHHHuangDHJiangZB

Combination Weight Loss (CagriSema) Extensive Research The Phase 3 REDEFINE 1 trial demonstrated that CagriSema (cagrilintide 2.4 mg plus semaglutide 2.4 mg) produced mean weight loss of 20.4% at 68 weeks in 3,417 adults with obesity or overweight without diabetes, compared to 14.9% with semaglutide alone, 11.5% with cagrilintide alone, and 3.0% with placebo

Report any new or unusual symptoms such as a neck lump, persistent hoarseness, or difficulty swallowing to your trial team promptly

Hippocampal CA1 betaCaMKII mediates neuroinflammatory responses via COX-2/PGE2 signaling pathways in depression