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In the analysis of ferroptosis-related genes in patients with UC, 26 differentially expressed genes have been identified that are significantly enriched in energy pathways and metabolism, with the top 10 hub genes from the protein-protein interaction network as interleukin 6 (IL6), prostaglandin-endoperoxide synthase 2 (PTGS2), hypoxia inducible factor 1 alpha (HIF1A), cluster of differentiation 44 (CD44), mucin 1 (MUC1), caveolin 1 (CAV1), nitric oxide synthase 2 (NOS2), C-X-C motif chemokine ligand 2 (CXCL2), stearoyl-CoA desaturase (SCD), and acyl-CoA synthetase long chain family member 4 (ACSL4) (62)

Conjunctival goblet cell quantification Goblet cell density was determined in male NOR mice at early (813 weeks) and established/advanced (2435 weeks) disease

doi: 10.1089/met.2023.0034 94 RasmussenMHHvidbergAJuulAMainKMGotfredsenASkakkebaekNEet al

Ramesh S, Arachchige ASPM (2023) Depletion of dopamine in Parkinsons disease and relevant therapeutic options: a review of the literature