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A study using an animal model exposed to THS under conditions that mimic exposure of humans suggests there are adverse effects of THS on liver, lung, skin healing, and behavior.In this study, THS delayed wound healing, increased hyperactivity on behavior tests, increased non-alcoholic fatty liver disease predisposing cirrhosis and cancer in liver, and stimulated excess collagen and cytokines production in lungs emulating inflammation-induced diseases such as COPD or asthma

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In 2009, Lucky Strike Silver (the variety marketed as "lighter") changed its UK pack from the quintessential red design to blue, albeit with a red outer covering around the packet