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Angew Chem Int Ed Engl 2008

The diagnostic process itself is clear-cut

But it can also include an agreement to supply or an offer to sell, even if no actual supply has taken place

For example the use of vitamin B12 for correct reasons improved by 10% (62% in phase 1 to 72% In phase 2) resulting in a 32% reduction in the number of patients inappropriately receiving it (521 to 352)