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Although human trials with dietary antioxidants have failed to reduce disease outcomes, it is important to recognize that these interventions are less efficacious in reducing oxLDL levels in humans than in rodent models

[32] Factors affecting formulations Various physical and chemical factors are involved in the formulation of topical emulsion or cream preparations, [37],[38],[39],[40],[41] some of which are briefly described below: Choice of emulsion type Oil-in-water emulsions are used for the topical application of water-soluble drugs, mainly for local effect