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Physiologically relevant concentrations of Nintedanib (100 nM) and Pirfenidone (100 M) reduce collagen I expression (J)

(1) Assessing fatty acid oxidation using addition of sequential substrates, (2) Mitochondrial respiration analysis with MiR05 respiration medium and sequential substrates, and (3) Assessment of complex II function using MiR05 supplemented with rotenone and complex II specific substrates

131 Intriguingly, pathways through the junctional complex or across the cells actively that participate in transport of ions, nutrients and other molecules could also be potential routes for drug delivery, which is discussed in detail in Section 3.1