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Quaternary structure analysis by AUC confirmed that the SLC complex, reconstituted in vitro, sediments as a heterodimer consisting of VpreB and 5 (~3.2 S)

Its beneficial effects cover a wide range of immunological functions, from improving the activity of macrophages and lymphocytes to regulating the adaptive immune response

Analytical size exclusion chromatography revealed a native molecular mass of 281 kDa (Figure 2C), indicative for a tetrameric quaternary structure of MSA-DH (266 kDa calculated theoretically)