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doi: 10.3390/ijms24021581 227 RahmanM

The catalytically-active U2/U6 structure is formed during spliceosome activation on the central PRP8 scaffold with the assistance of activation-associated proteins such as CDC5L, PLRG1, RBM22, SKIP, and WBP11(NPW38BP) 12,18,19,100,101,102