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Notely, systematic reviews have failed to demonstrate consistent or sustained benefits (Figure 2)

After vortexing (30 min, 4 C) and centrifugation (1,000 g, 20 min, 0 C), aqueous and organic phases were separated, dried, and stored at 80 C

Hydration-only formulas using normal saline or lactated Ringers solution remain essential for straightforward clinical situations such as dehydration resulting from acute illness, heat exposure, or strenuous athletic competition