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Oct 9: In a relatively rare move, the FDA went against the recommendation of one of its advisory committees, rejecting a bid by Alnylam to expand Onpattro (patisiran)s label to cardiomyopathy of transthyretin-mediated amyloidosis

Wei et al., 2017b)

Despite the lack of relevant clinical improvements of CXCR2 inhibition in COPD, recent studies have been evaluating the use of superior antagonists, with dual inhibition of CXCR1 and CXCR2, that may present higher potency