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These studies point out the need to consider the form of supplemental selenium, biologically active biomarkers and their function versus tissue selenium levels, short-term versus long-term changes in biomarkers, and repletion of deficient subjects versus maintenance of status of selenium-adequate subjects when interpreting the results of such studies

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Shammas H, Kloster Fog C, Klein P, Koustrup A, Pedersen MT, Bie AS, et al

Both semaglutide and tirzepatide are GLP-1-based injectable weight loss medications, but tirzepatide is a dual GIP/GLP-1 receptor agonist, meaning it activates an additional hormonal pathway that amplifies metabolic effects