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Co-enzyme B12 also interacts with the enzyme methionine synthase (5-methyltetrahydrofolate-homocysteine methyltransferase), required for the conversion of homocysteine to methionine, which is essential for folic acid metabolism and the formation of thymine, which is a component of DNA

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As a biological macromolecule, how SOD enzyme enters the human body through the cell barrier, but also whether it can be absorbed and utilized by human gastric juice and epidermis, is still inconclusive