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doi: 10.3350/cmh.2021.0308 100 HuCPangBLinGZhenYYiH

R Substrates conjugated with amino acids include: Benzoic acid (from toluene exposure, food preservatives, and gut bacterial metabolism of polyphenols), conjugated with glycine to form hippuric acid R Bile acids (conjugated with glycine or taurine for proper emulsification and excretion) R NSAIDs and other acyl group drugs Phenylacetic acid (from phenylalanine metabolism), conjugated with glutamine to form phenylacetylglutamine R Salicylic acid (aspirin metabolite), conjugated with glycine to form salicyluric acid R Glycine conjugation is the most common amino acid conjugation

Also, at all visits, a blood aliquot of 7 mL was drawn for complete blood cell counts, chemistry, and lactate dehydrogenase

A similar approach was then used for the data acquired herein with POPE 13 C-MRS in mice