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Models were corrected for the baseline covariates sex, age (B-splines), relative time of inclusion (B-splines), and second antihypertensive drug class, as well as 1-year values for socioeconomic group, municipality, living alone, loop diuretic use, diabetes mellitus, hyperlipidaemia, depression, stroke, head trauma, atherosclerosis, chronic obstructive pulmonary disease and liver disease

Typically, molecules are found to be highly water soluble if the ratio of their total number of carbon atoms to the number of hydrophilic functional groups is less than about 31

In the phase 2 trial, 41% to 63% of participants receiving cagrilintide (0.3 to 4.5 mg) experienced gastrointestinal adverse events, compared to 32% with placebo

We are unable to provide any dosing instructions