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RUO materials are not subject to FDA pre-market approval for human administration, cannot be used as drug ingredients in compounding, and are not intended for diagnostic, therapeutic, or veterinary use

For the LC-MS aliquot, 50 L of acyl-CoA internal standard was added

Results are presented as a ratio between +1 and 1

Neuroactive peptides work through mechanisms such as brain-derived neurotrophic factor (BDNF) upregulation, HGF/c-Met signaling, and modulation of monoamine neurotransmitters (Table 4)