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Transport across the BBB is facilitated by specific proteins, such as low-density lipoprotein receptor-related proteins 1 (LRP-1) and P-glycoprotein, which mediate the efflux of A into the plasma [36, 37]

[DOI] [PubMed] [Google Scholar] [222].Saini V, Cumming BM, Guidry L, Lamprecht DA, Adamson JH, Reddy VP, Chinta KC, Mazorodze JH, Glasgow JN, Richard-Greenblatt M, Gomez-Velasco A, Bach H, Av-Gay Y, Eoh H, Rhee K, Steyn AJC, Ergothioneine maintains redox and bioenergetic homeostasis essential for drug susceptibility and virulence of Mycobacterium tuberculosis, Cell Rep

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T-Cells from HLA-B*57:01+ human subjects are activated with abacavir through two independent pathways and induce cell death by multiple mechanisms