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Such metabolic rewiring towards increased aerobic glycolysis also formed the basis for -glucan-induced trained immunity of monocytes and was associated with epigenetic histone modifications and increased expression of genes involved in glycolysis triggered by the AKT-mTOR-HIF1 pathway (Sohrabi et al., 2018

Table 2 shows the computed AIC and BIC values, illustrating that the reduced model returns a much higher score than the triad and comproportionation models

These redox-responsive nanoparticles demonstrated superior gene transfection and tumor suppression compared to redox-insensitive carriers