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Hansson, E

Ethics statement The studies involving human participants were reviewed and approved by the Research Ethics Committee of the Second Affiliated Hospital of Chongqing Medical University, China (202164)

A better understanding of the genotype and phenotype relationship involved in LS could help with better diagnosis and early treatment of the disease, subsequently resulting in prolonging the lives of patients with LS

Careful consideration should be given to the appropriate control or sham groups, blinding of researchers, and randomization techniques during preclinical investigations