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PPAR activator MHY2013 significantly reduced lipid accumulation in TECs and attenuated renal fibrosis in senescent rats [41], which further emphasized the importance of PPAR and FAO in regulating renal lipid homeostasis

431 Primary human fibroblasts from Friedreichs Ataxia patients are highly sensitive to erastin, a small molecule inhibitor of system Xc , and the ferroptosis inhibitor Fer-1 protects fibroblast cells from damage caused by ferroptosis