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Additional information Peer review information: Nature Communications thanks Paul Baird and the other anonymous reviewer(s) for their contribution to the peer review of this work

In: Therapy of Movement Disorders Current Clinical Neurology Reich SG, Factor S (eds) Springer Nature International Publishing Switzerland 2019 Vasconcelos OM

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Taken together, these findings indicated that hepsin / mice experience heightened oxidative stress in the early stages of APAP exposure, suggesting that endogenous hepsin might protect against toxicity during the early stages of APAP exposure, thereby significantly influencing survival outcomes in drug-induced toxicity cases