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Safety Profile & Reported Adverse Effects The Phase 2b trial (PMID: 23714218) reported a favorable short-term safety profile with no serious adverse events attributed to AOD-9604

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Not necessarily so, according to Robert Barker and Richard Coutts, founders of Baca Architects, who have spent the past decade dedicated to developing building strategies that can work with water, rather than against it, and whose thinking has resulted in a timely new book, Aquatecture

While no research yet shows a connection to Hashimotos, I wanted to make note that in some cases, individuals may have normal blood levels of folate, but the folate may not be getting to the brain due to autoimmune folate receptor antibodies (FRAs), which block the transport of folate into the cerebral spinal fluid (CSF)