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Why this trial matters: First bispecific + CD38 combo to show superior PFS and OS in Phase III in RRMM Potential new standard of care as early as second-line Demonstrates deep responses, high MRD-negativity, and durable outcomes First-line Strategies in BRAF V600E-Mutant mCRC: Real-World Evidence Signals Treatment Priorities In a real-world retrospective cohort of patients with BRAF V600E-mutant metastatic colorectal cancer (mCRC), frontline chemotherapy plus anti-VEGF therapy was associated with the longest survival outcomes, while BRAF-targeted strategies showed promising response rates, emphasizing the need for tailored therapy and prospective validation

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Level of evidence C - Multiple studies with limitations or conflicting results Read more Please see Table 1 for your response

Syringe Units = Desired Dose (mg)Concentration (mg/mL) 100 Example: a 0.5 mg dose at 5 mg/mL = (0.5 5) 100 = 10 units