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1 H NMR (400 MHz, DMSO- d 6 ) 12.30 (s, 1H), 10.99 (s, 1H), 7.65 (dd, J = 7.3, 1.3 Hz, 1H), 7.607.47 (m, 2H), 7.40 (d, J = 7.6 Hz, 1H), 6.72 (s, 1H), 5.13 (dd, J = 13.3, 5.1 Hz, 1H), 4.30 (dd, J = 57.6, 17.4 Hz, 3H), 4.06 (s, 2H), 3.92 (t, J = 14.5 Hz, 1H), 3.11 (s, 2H), 3.01 (t, J = 11.7 Hz, 1H), 2.982.85 (m, 1H), 2.72 (dd, J = 13.1, 9.5 Hz, 1H), 2.642.54 (m, 2H), 2.492.27 (m, 3H), 2.071.94 (m, 1H), 1.80 (s, 2H), 1.64 (d, J = 3.1 Hz, 4H), 1.54 (d, J = 12.1 Hz, 1H), 1.38 (dd, J = 23.0, 13.7 Hz, 1H), 1.18 (d, J = 4.8 Hz, 9H)

Infection represents the most serious risk