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The 24-week interim results for those who were previously treated with tesofensine 0.5 mg in TIPO-1 showed a total mean weight loss of between 13 kg and 14 kg over 48 weeks of treatment

Particularly, PARP14 can promote glycolysis in different tumor models, such as human hepatocellular carcinoma (HCC), by maintaining reduced PKM2 activity (Zhu et al., 2022)