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Multiple reviews have highlighted ferroptosis as a promising target for various neurological disorders, and these reviews have also summarized the major regulators and associated studies in this field (178,200,201)

Risks for astaxanthin supplements Avoid taking astaxanthin if you're allergic or sensitive to it

Frataxin depletion does not cause overproduction of superoxides On the basis of the putative respiratory chain impairment and/or the iron-associated Fenton chemistry presumably resulting from iron mishandling, it has been inferred that frataxin depletion should result in overproduction of oxidant species

Hemolytic anemia and metabolic acidosis: think about glutathione synthetase deficiency