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A Fibroblast Growth Factor 21-Pregnane X Receptor Pathway Downregulates Hepatic CYP3A4 in Nonalcoholic Fatty Liver Disease

Cardiolipin can be oxidized by ROS or by the cardiolipincytochrome c complex (Kagan et al., 2005)

SCH51344, though not used clinically, led to the identification of crizotinib, a widely used dual Met/ALK inhibitor, as a potent inhibitor of MTH1 activity