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2.3 Statistical analysis Progression-free survival (PFS) was defined as the time from initiation of systemic therapy to the date of documented disease progression or last patient contact (censored)

Intracellular bacterial growth assay After 1 day of infection with Mtb strains, pulsed or unpulsed BMDMs were co-incubated with CD8 + T cells for 3 days and intracellular c.f.u

In agreement with this, we observed the highest expression of PrP in cholangiocarcinoma nodes in the liver of Atp7b / mice, whereas PrP depletion almost completely prevented tumor growth