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GSH, an antioxidant, protects cancer cells from oxidative stress via the GSH/GSSG cycle, which decreases intracellular ROS levels and transforms NADPH to NADP+ (Fig

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Statistical Analysis Statistical analysis was performed by parametric one-way analysis of variance (ANOVA), with the post hoc NewmanKeuls test, or non-parametric KruskalWallis test, followed by the Mann-Whitney U test to compare groups

Nevertheless, research directly elucidating the causal effects of specific SCFAs on the gut microbial community in hyperuricemic patients remains limited, warranting further exploration to fully understand their potential and mechanisms of action