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Activation of a receptor by its endogenous agonist may activate G protein- and -arrestin-mediated signaling, phosphorylation of the receptor by one or more protein kinases, desensitization, and receptor internalization, which is then followed by either recycling or degradation of the receptor

The atomic models used in this paper were obtained from the Protein Data Bank under accession codes 5VI5, 6BZO and 6FLQ

Cancer Res 41(9 Pt 1):36533657 Committee ES, Hardy A, Benford D et al (2017) Guidance on the risk assessment of substances present in food intended for infants below 16 weeks of age