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Protein redox chemistry: Post-translational cysteine modifications that regulate signal transduction and drug pharmacology

Future perspectives and conclusion The information gathered in this review indicates that the TRPM2 channel modulates microglial function and that microglial TRPM2 emerges as a key element and potential therapeutic target across diverse neurological diseases

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It would be worthwhile to understand how the circadian system operates in contexts of accelerated aging, such as in progeroid syndromes, both in preclinical models and in humans, to uncover potential shared mechanisms