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A close examination into the available human research on glutamine makes it more challenging to characterize glutamines potential

Acrylamide, a popular cysteine-targeting warhead widely used in approved covalent drugs due to its superior selectivity and exellent pharmacokinetic properties 54 , was incorporated as well

PTT, in contrast, employs NIR photothermal agents that convert light energy into heat (4060 C), denaturing proteins and disrupting membranes independently of bacterial metabolic state

Using the known second order rate constant for the reaction (~1 M 1 s 1 ) and estimated GSH concentration (~1 mM), the first order rate constant for this reaction would be 0.001 s 1